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More events occur in patients with normal or mildly abnormal functional tests, as shown by latest analysis of PROMISE study.

UK NICE guidance recommends CT coronary angiography for diagnosis of CAD in patients with atypical or typical angina in its 2016 update of CG95 (Chest pain of recent onset: assessment and diagnosis).

In this prospective study, led by Prof Newby of University of Edinburgh, evaluated the use of 18F-NaF and 18F-FDG tracers in identification of ruptured and high-risk atherosclerotic plaques using PET-CT.

This latest document rates the appropriateness of different imaging modalities for various indications to exclude stable ischemic heart disease.