More events occur in patients with normal or mildly abnormal functional tests, as shown by latest analysis of PROMISE study.
UK NICE guidance recommends CT coronary angiography for diagnosis of CAD in patients with atypical or typical angina in its 2016 update of CG95 (Chest pain of recent onset: assessment and diagnosis).
An important study comparing CTA and combined CTA+CTP with SPECT MPI and invasive angiography.
Very high calcium score of >1000 in asymptomatic patients were found to be associated with >8 fold greater mortality compared with those with absent score over a mean follow-up period of 5.6 years.